Resveratrol's magic may be in reducing inflammation

Photo: Joseph Leonardo/Flickr CC

TNF, the protein linked to all sorts of age-related physical ailments, is suppressed by resveratrol –found in red wine and other foods — a study finds:

The study, published online ahead of print in the Journal of Clinical Endocrinology & Metabolism, finds blood samples from those who took resveratrol showed suppression of the inflammatory protein tumor necrosis factor, which causes insulin resistance and the risk of developing diabetes. Blood samples from those who received the placebo showed no change in the pro-inflammatory markers.

via Resveratrol may suppress inflammation – UPI.com.

In cognitive tests, potheads tend to get it right, eventually

Photo: Bryan Brenneman/Flickr CC

Columbia University scientists recently reported that chronic tokers — those blazing morning, noon and night — do just fine on cognitive performance tests.

All they need is a bit more time.

From an abstract at PubMed:

“The overall response accuracy on the word recognition and working memory tasks was unaffected by marijuana, although smoked marijuana did increase the amount of time participants needed to complete these tasks.”

Sci-Tech Heretic readers will recall a similar finding with marijuana users who did fine in driving simulators, perhaps because they drove more slowly.

via Neurophysiological and cognitive effects of smoked… [Pharmacol Biochem Behav. 2010] – PubMed result.

Pot is a pain buster, Texas docs say

Needs relief. Photo: Elvert Barnes/Flickr CC

Diabetics and others with chronic pain caused by peripheral nerve damage, might find relief in a pot derivative, according to docs at the Texas M.D. Anderson Cancer Center.

Last week the researchers announced a finding that the cannabinoid, MDA19, reduces neuropathic pain, “without producing adverse effects in the central nervous system.”

In other words, using the cannabinoid alone reduced pain in rats, without getting them stoned — an undesirable effect, as the docs see it.

The synthetic cannabinoid (cannabis-related) compound, called MDA19, seems to avoid side effects by acting mainly on one specific subtype of the cannabinoid receptor. “MDA19 has the potential for alleviating neuropathic pain without producing adverse effects in the central nervous system,” according to the study by Dr Mohamed Naguib of The University of Texas M.D. Anderson Cancer Center.

via Marijuana Derivative Could Be Useful for Pain Treatment Blocks Neuropathic Pain without Undesired Side Effects.

Coffee prevents cancer of the head and neck

Good for her. Photo: Vladimer Shioshvili/Flickr CC

Cancers of the mouth and throat are among the deadliest. But if, like me, you drink coffee by the bucket-full, your chances of developing the disease are 40 percent less that non-coffee drinkers.

“Since coffee is so widely used and there is a relatively high incidence and low survival rate of these forms of cancers, our results have important public health implications that need to be further addressed,” Huntsman Cancer Institute (University of Utah) investigator lead researcher Mia Hashibe said in a release this afternoon.

This news comes on the heels of a report last week that coffee might reduce your risk for diabetes

In other words, if you’ve been following Dr. Andrew Weil’s snake oil advise, and been feeling superior for not being a coffee drinker, you’ve again been misled by the self-appointed sage of alternative medicine.

U. of Utah's Mia Hashibe makes a startling epidemiological finding. Photo: American Association for Cancer Research

More from the announcement:

Using information from a pooled-analysis of nine studies collected by the International Head and Neck Cancer Epidemiology (INHANCE) consortium, participants who were regular coffee drinkers, that is, those who drank an estimated four or more cups a day, compared with those who were non-drinkers, had a 39 percent decreased risk of oral cavity and pharynx cancers combined.

Data on decaffeinated coffee was too sparse for detailed analysis, but indicated no increased risk. Tea intake was not associated with head and neck cancer risk.

The association is more reliable among those who are frequent, regular coffee drinkers, consuming more than four cups of coffee a day.